Synthesis and Characterization of Green Zinc-Metal-Pillared Bentonite Mediated Curcumin Extract (Zn@CN/BE) as an Enhanced Antioxidant and Anti-Diabetes Agent

Green zinc-metal-pillared bentonite mediated curcumin extract (Zn@CN/BE) was synthesized and characterized as a low-cost multifunctional (curcumin-based phytochemicals, zinc-capped curcumin, zinc/curcumin complexes, zinc-pillared bentonite) antioxidant antidiabetic agent with enhanced activity. The activities of the Zn@CN/BE structure were assessed in comparison ZnO individual components presence miglitol acarbose commercial drugs controls. validated remarkable against common oxidizing radicals (nitric oxide (94.7 ± 1.83%), DPPH (96.4 1.63%), ABTS (92.8 1.33%), superoxide (62.3 1.63 %)) inhibition main enzymes (porcine α-amylase (89.3 1.13%), murine (70.8 1.54%), pancreatic α-Glucosidase (99.3 1.23%), intestinal (97.7 1.24%), amyloglucosidase (98.4 1.64%)). reported are higher than studied ascorbic acid well drugs. This enhancement effect assigned to impact zinc pillaring process within curcumin/bentonite host, which induced stability, dispersions, interactive interface essential active compounds addition solubility release rate intercalated extract. paper recommends application an enhanced, low-cost, biocompatible, safe, simply produced agent.